Saladax Biomedical develops novel diagnostic assays for the practical delivery of personalized medicine and companion diagnostics.
Our proprietary diagnostic tests improve the efficacy of drug treatment through optimized dosing. Saladax's initial focus is in the field of oncology drug dose optimization, with a portfolio
of thirteen proprietary cancer drug assays in various stages of development.
Most cancer drugs have a narrow therapeutic index and a dose-limiting toxicity profile that make these drugs ideal candidates for dose management through the measurement of drug concentration in blood. Saladax's simple MyCare™ blood tests enable an oncologist to optimize dosing for target drug levels to achieve optimal balance of efficacy and toxicity, where the loss of this balance can have devastating effects on patients.
The first MyCare assay available to the oncology community is for one of the most common anticancer drugs, 5-fluorouracil, commonly referred to as 5-FU. It is offered commercially in North American by Myriad Genetics under the trade name, OnDose.™ FALCO biosystems is preparing for launch of the My5-FUTM as exclusive distributors for the Japanese market.. The My5-FU assay is CE-marked and available for commercialization in the European Union.
The Saladax portfolio extends beyond oncology, with two Central Nervous System (CNS) disorder drug management tests. Like many oncology drugs, some anti-psychotics and anti-depressants have a narrow therapeutic window and dose limiting toxicity.
The Company's MyCare technology platform is broad and flexible, enabling wide application in many therapeutic categories and for multiple applications. It offers the potential to achieve benefits such as optimizing dosing, solving narrow therapeutic index problems, and achieving optimal efficacy/toxicity balance.
Saladax is a valuable partner for pharmaceutical and biotechnology companies in the development of companion diagnostics (CDx), addressing numerous risks and challenges in the new drug development process. We are ISO 13485:2003 certified.